抽象的

The creation of vascular disease models for the purpose of investigating the pathogenesis and causation of rare vascular diseases.

Henry Ady

The utility of rare monogenetic vascular disease modeling in this landscape is beginning to emerge as the medical field strives forward amid a new era of integrated technologies like bio printing and biological material development heralded by next-generation sequencing (NGS). These patient-specific models are at the forefront of modern personalized medicine because they are genetically simple and can be used for a wider range of applications. Rare vascular diseases account for a significant portion of the global burden of rare diseases on healthcare systems as a whole. The severity and chronic nature of the disease, as well as the lengthy diagnostic process that affects people of all ages, contribute to the disease’s high costs. Because of their complexity, sophisticated disease models and integrated strategies involving multidisciplinary teams are required.