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Lipid disorders in hospitalized patients with chronic kidney disease

Eleni Chelioti

Kidney disease patients often present with dyslipidemia. Lipid profile abnormalities differ between spectrums of kidney disease and are aggravated by comorbidities such as diabetes. Dyslipidemia is considered an important contributor to the increased cardiovascular mortality and constitutes an essential therapeutic target   for nephrology patients.  The propose of this study was to determine the lipid abnormalities of kidney disease patients who were admitted to our Nephrology ward in the past five years. We studied 450 patients with chronic kidney disease and hypertension (180 women, 40%  and 270 men 60% , mean age 65±25 years). Mean eGFR was 40±12 ml/min/1.73m2 The parameters determined and analyzed were: total-cholesterol  (<180mg/dl), LDL- cholesterol (<100mg/dl) and triglycerides ( <150mg/dl). All patients were receiving treatment for regulating dyslipidemia. The percentage of patients with total cholesterol, LDL-cholesterol and triglycerides within the recommended targets were 30%, 15% and 36% respectively.  Total cholesterol above the  recommended targets had the 315 of patients (189 men, 60% and 126 women, 40%). 382 patients had  LDL- cholesterol over the targets (48 men, 65% and 134 women, 35%). High levels of triglycerides has been found at 288 patient (167men ,58% and 121 women,  42%). There is a low percentage of our patients that non achieved the recommended targets, despite the fact  that they receiving treatment and remain disregulated. Certainly in patients with chronic kidney disease and dyslipidemia the periodical monitoring of the lipid profile is required for a  proper regulation.