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Cost effectiveness of fractional flow reserve-guided percutaneous coronary intervention

F Abnousi, C Yong & W Fearon

In recent years, fractional flow reserve (FFR) has become accepted as a clinically effective tool for guiding decisions about percutaneous coronary intervention (PCI). FFR poses a unique alternative to stress testing or angiography-guided PCI, in that it can interrogate the ischemic potential of an individual vessel on an impromptu basis once an angiogram is in progress, offering immediate data for decision making. With its recent greater adoption across the USA, its cost–effectiveness has become an important consideration. There have been a few key analyses over the last decade demonstrating the cost–effectiveness of FFR-guided PCI; we review the major cost– effectiveness analyses, showing the economic utility of FFR-guided PCI for the modern interventionalist.