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Clinical Characteristics and Results of Hospital-Acquired Acute Kidney Injury in Noncritical Care Settings

Scott Sutherland*

Australian statistics on the prevalence and prognosis of noncritically unwell patients’ hospital-acquired acute kidney injury (HA-AKI) are scarce. The purpose of this study was to define HA-AKI and evaluate how nephrology visits affected the results. All noncritically unwell patients with HA-AKI who were hospitalised to a major tertiary hospital in 2018 were followed up from the time of admission until they were discharged. The Kidney Disease Improving Global Outcomes (KDIGO) criteria were used to define HA-AKI. The clinical characteristics of individuals who developed HA-AKI and the variations in these characteristics according to nephrology consultation were the study’s main findings. The study included 222 noncritically ill patients in total. The included patients had a mean age of 74.8 15.8 years, and 57.2% of them were female. While the majority of patients (92%) were classified as having KDIGO stage 1, 14% had nephrology consultations, and 80% had recovered their kidney function completely or in part by the time they were discharged. Receiving nephrology consultation was linked to lower recovery rates (65% versus 83%), longer hospital stays (10 versus 5 days), and higher blood creatinine values at release (152 versus 101 mol/L). Between those who had nephrology consultations and those who did not (13% versus 11%, P = 0.754), there was no difference in mortality rates. Our research shows that a sizable fraction of noncritically ill patients develop mild AKI during hospitalisation and recover their renal function well, Despite the fact that the severity of AKI and length of hospitalisation were linked to nephrology therapies, a larger study is needed to fully grasp how these interventions affect clinical outcomes like hospital readmission and mortality.

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