抽象的

A Novel Guide Wire Facilitates Percutaneous and Nofluoroscopic Procedure for Atrial Septal Defect Closure

Guangzhi Zhao, Shouzheng Wang, Yongquan Xie, Fengwen Zhang, Cheng Wang and Xiangbin Pa

Objective: The purpose of this pilot study was to assess the safety and efficacy of a novel ultrasound guided wire for the treatment of patients with atrial septal defect (ASD) who underwent percutaneous atrial septal defect closure using transthoracic echocardiographic (TTE) guidance only.

Materials and methods: From November 2017 to December 2017, 10 patients with congenital ASD were recruited for echo-guiding occlusion with a new designed wire specialized for percutaneous and no-fluoroscopic procedure. The novelty of this wire lies in the elastic spindleshaped tip which helps with precise positioning under ultrasound while reducing difficulty and complications. Operations were performed by 3 doctors who had performed no more than 10 echo-guided cases. Operative successful rate was used as the main evaluation index, Secondary evaluation index included operative time, the number of times guide wire or delivery system dropped into right atrial, frequency of arrhythmia, the number of times guide wire went through tricuspid valve, cardiac perforation, cardiac tamponade and peripheral vascular complications.

Result: All 10 patients successfully underwent percutaneous and no-fluoroscopic atrial septal defect closure with the novel wire. The mean operation time was 20.20±8.904 minutes. The followup time was 3 months and no severe complication occurred. Conclusion: This pilot study demonstrated that the new ultrasound guided wire can be precisely positioned under ultrasound and can facilitate percutaneous and no fluoroscopic procedure safely and effectively.